Cosmosmagazine.com | Tuesday, 9 October 2007 | Blood transfusions may do more harm than good for many patients because banked blood begins to lose a key gas almost immediately after it is donated, claim researchers.
Nitric oxide facilitates the transfer of oxygen from red blood cells to tissues, but it begins to be lost within three hours of being banked, according to two studies from the Duke University Medical Center in North Carolina, USA.
"The issue of transfused blood being potentially harmful to patients is one of the biggest problems facing American medicine," said Jonathan Stamler, a professor of cardiovascular and pulmonary medicine and part of the team behind the studies reported this week in the U.S. journal, the Proceedings of the National Academy of Sciences.
"In principle, we now have a solution to the nitric oxide problem – we can put it back – but it needs to be proven in a clinical trial," he said.
Increased blood flow
Stamler's team has already managed to increase blood flow to the hearts of oxygen-deprived dogs after they added nitric oxide back to banked blood. The next step is to see if this technique also works in humans.
A number of recent studies have found that patients who receive blood transfusions have higher incidences of heart attack, heart failure, stroke and even death. But this is the first study to identify why.
"Nitric oxide opens up the tiny blood vessels, allowing red blood cells to pass and deliver oxygen," Stamler said. "If the blood vessels cannot open, the red blood cells back up in the vessel and tissues go without oxygen. The result can be a heart attack or even death."
Nitric oxide might also influence the flexibility of the saucer-shaped blood cells. The studies also found that the red blood cells become stiffer as nitric oxide levels decrease, making it hard for them to squeeze through tiny blood vessels.
www.AstroDigi.com (Nino Guevara Ruwano)
tory burch outlet, michael kors outlet, louis vuitton outlet, louis vuitton, air max, prada handbags, longchamp outlet, longchamp handbags, louis vuitton outlet stores, michael kors outlet, louboutin shoes, nike shoes, burberry outlet, chanel handbags, true religion jeans, nike free, polo ralph lauren outlet, true religion jeans, prada outlet, oakley sunglasses cheap, coach outlet, ray ban sunglasses, air max, longchamp handbags, kate spade outlet, louis vuitton outlet, polo ralph lauren, ray ban sunglasses, christian louboutin, oakley sunglasses, gucci outlet, michael kors outlet, michael kors outlet, coach factory outlet, burberry outlet, louboutin outlet, michael kors outlet, coach outlet store online, tiffany and co, louis vuitton handbags, kate spade handbags, louboutin, tiffany and co, jordan shoes, coach purses, michael kors outlet, oakley sunglasses
ReplyDeletenike free pas cher, lululemon, polo ralph lauren, michael kors, new balance pas cher, ralph lauren, ray ban pas cher, timberland, hollister, air max, mulberry, nike roshe run, vans pas cher, air max, sac hermes, nike blazer, longchamp, oakley pas cher, sac louis vuitton, ray ban sunglasses, vanessa bruno, north face, nike air max, louis vuitton uk, louboutin, hogan outlet, air max pas cher, abercrombie and fitch, air jordan, air force, converse pas cher, sac louis vuitton, hollister, true religion outlet, north face, michael kors pas cher, louis vuitton, sac guess, nike roshe, michael kors, nike tn, sac longchamp, true religion outlet, barbour, sac burberry, nike free, polo lacoste, nike trainers
ReplyDeletegiuseppe zanotti, ugg boots, hollister, longchamp, wedding dresses, canada goose, birkin bag, chi flat iron, reebok outlet, ugg boots, abercrombie and fitch, bottega veneta, canada goose, nfl jerseys, insanity workout, ugg australia, marc jacobs, uggs outlet, vans shoes, north face jackets, ferragamo shoes, p90x, ugg pas cher, canada goose outlet, soccer shoes, canada goose jackets, north face outlet, beats by dre, canada goose, ugg, jimmy choo outlet, new balance shoes, nike huarache, ugg boots, rolex watches, herve leger, celine handbags, nike roshe run, ghd, babyliss pro, mont blanc, mac cosmetics, uggs, mcm handbags, valentino shoes, instyler, lululemon outlet, soccer jerseys, asics running shoes
ReplyDeletevans, moncler, ralph lauren, links of london, parajumpers, hollister, juicy couture outlet, converse shoes, oakley, pandora charms, toms shoes, swarovski, louboutin, hollister, coach outlet store online, ugg, louis vuitton, pandora charms, gucci, baseball bats, moncler, thomas sabo, lancel, pandora jewelry, timberland boots, hollister clothing store, rolex watches, canada goose uk, moncler outlet, moncler, iphone 6 cases, wedding dresses, air max, canada goose, juicy couture outlet, canada goose, moncler, ugg, swarovski crystal, ray ban, supra shoes, karen millen, converse, air max, moncler, moncler, montre homme
ReplyDeleterolex watches
ReplyDeletecoach outlet online
mizuno running shoes
tiffany and co
cheap soccer jerseys
woolrich outlet store
black friday 2015
asics,asics israel,asics shoes,asics running shoes,asics israel,asics gel,asics running,asics gel nimbus,asics gel kayano
ray ban sunglasses
true religion jeans outlet
tory burch sale
pandora outlet
ferragamo shoes
canada goose coats
tiffany outlet
ferragamo shoes sale
louis vuitton bags
michael kors handbags wholesale
ralph lauren outlet
oakley sunglasses
mm1224
2016-06-28keyun
ReplyDeletelouis vuitton purses
michael kors purses
ralph lauren polo shirts
burberry sale
ray ban sunglasses outlet
polo ralph lauren outlet
michael kors outlet online
polo ralph lauren
louis vuitton outlet stores
cheap oakley sunglasses
adidas wings
louis vuitton outlet
coach outlet
celine outlet
lebron 12
michael kors outlet
michael kors outlet
michael kors outlet
jordan retro 13
toms shoes
air max 95
nike sb janoski
nike running shoes for men
nfl jerseys
cheap oakleys
longchamp outlet
coach factory outlet online
hollister clothing
asics running shoes
michael kors canada outlet
coach factory outlet online
fitflop sale
michael kors outlet online
louis vuitton handbags
michael kors handbags
mont blanc pen
tory burch outlet
jordan 6s
montblanc pens
denver broncos jerseys
ReplyDeletesteelers jerseys
new york knicks
michael kors handbags
cowboys jerseys
nike tn pas cher
new balance outlet
michael kors outlet
browns jerseys
nike store uk
Coach Outlet ED Hardy Outlet Coach Outlet Store Online Kate Spade Outlet Cheap Jordans Coach Purses Coach Outlet Kate Spade Outlet Toms Outlet Louis Vuitton
ReplyDelete